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Détail de l'auteur
Auteur J. Richard Heys
Documents disponibles écrits par cet auteur
Faire une suggestion Affiner la recherchePreparation of compounds labeled with tritium and carbon-14 / Rolf Voges
Titre : Preparation of compounds labeled with tritium and carbon-14 Type de document : texte imprimé Auteurs : Rolf Voges, Auteur ; J. Richard Heys, Auteur ; Thomas Moenius, Auteur Editeur : New York : Wiley Année de publication : 2009 Importance : XVI, 664 p. Présentation : ill. Format : 25 cm ISBN/ISSN/EAN : 978-0-470-51607-2 Note générale : Bibliogr.p.634-637. -Index Langues : Anglais (eng) Mots-clés : Composés organiques -- Synthèse
Sciences de la santé
Tritium
Carbone -- IsotopesIndex. décimale : 66.09 Réactions chimiques. Procédés chimiques et biochimiques particuliers Résumé : Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals.
Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include:
* Formulation of synthetic strategies for preparing labeled compounds
* Isotope exchange methods and synthetic alternatives for preparing tritiated compounds
* In-depth discussion of carbon-14 building blocks and their utility in synthesis
* Preparation of enantiomerically pure isotopically labeled compounds
* Applications of biotransformations
Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.Note de contenu : Au sommaire:
1. Introduction
2. Strategies for Target Preparation
3. Preparation of Tritium-Labeled Compounds by Isotope Exchange Reactions
4. Preparation of Tritium-Labeled Compounds by Chemical Synthesis
5. Barium [14C]Carbonate and the Preparation of Carbon-14-Labeled Compounds via One-Carbon Building Blocks of the [14C]Carbon Dioxide Tree
6. Preparation of Carbon-14-Labeled Compounds via Multi-Carbon Building Blocks of the [14C]Carbon Dioxide Tree
7. Preparation of Carbon-14-Labeled Compounds via the [14C]Cyanide Tree
8. Preparation of Carbon-14-Labeled Compounds via the [14C2]Acetylene Tree
9. Preparation of Carbon-14-Labeled Compounds via the [14C]Cyanamide Tree
10. Reconstitution Strategies
11. Preparation of Enantiomerically Pure Compounds Labeled with Isotopes of Hydrogen and Carbon
12. Biotransformations in the Preparation of Compounds Labeled with Carbon and Hydrogen IsotopesPreparation of compounds labeled with tritium and carbon-14 [texte imprimé] / Rolf Voges, Auteur ; J. Richard Heys, Auteur ; Thomas Moenius, Auteur . - New York : Wiley, 2009 . - XVI, 664 p. : ill. ; 25 cm.
ISBN : 978-0-470-51607-2
Bibliogr.p.634-637. -Index
Langues : Anglais (eng)
Mots-clés : Composés organiques -- Synthèse
Sciences de la santé
Tritium
Carbone -- IsotopesIndex. décimale : 66.09 Réactions chimiques. Procédés chimiques et biochimiques particuliers Résumé : Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals.
Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include:
* Formulation of synthetic strategies for preparing labeled compounds
* Isotope exchange methods and synthetic alternatives for preparing tritiated compounds
* In-depth discussion of carbon-14 building blocks and their utility in synthesis
* Preparation of enantiomerically pure isotopically labeled compounds
* Applications of biotransformations
Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.Note de contenu : Au sommaire:
1. Introduction
2. Strategies for Target Preparation
3. Preparation of Tritium-Labeled Compounds by Isotope Exchange Reactions
4. Preparation of Tritium-Labeled Compounds by Chemical Synthesis
5. Barium [14C]Carbonate and the Preparation of Carbon-14-Labeled Compounds via One-Carbon Building Blocks of the [14C]Carbon Dioxide Tree
6. Preparation of Carbon-14-Labeled Compounds via Multi-Carbon Building Blocks of the [14C]Carbon Dioxide Tree
7. Preparation of Carbon-14-Labeled Compounds via the [14C]Cyanide Tree
8. Preparation of Carbon-14-Labeled Compounds via the [14C2]Acetylene Tree
9. Preparation of Carbon-14-Labeled Compounds via the [14C]Cyanamide Tree
10. Reconstitution Strategies
11. Preparation of Enantiomerically Pure Compounds Labeled with Isotopes of Hydrogen and Carbon
12. Biotransformations in the Preparation of Compounds Labeled with Carbon and Hydrogen IsotopesExemplaires
Code-barres Cote Support Localisation Section Disponibilité Etat_Exemplaire 054356 66.09 VOG Papier Bibliothèque Centrale Génie Chimique Disponible En bon état