| Titre : | Microcalorimetry of macromolecules : the physical basis of biological structures |
| Auteurs : | Peter L. Privalov, Auteur |
| Type de document : | texte imprimé |
| Editeur : | New York : John Wiley & Sons, 2012 |
| ISBN/ISSN/EAN : | 978-1-118-10451-4 |
| Format : | VI, V, 393 p. / ill. / 24 cm |
| Note générale : | Bibliogr. p. 383. - Index |
| Langues : | Anglais |
| Index. décimale : | 536.6 (Mesure de la quantité de chaleur. Calorimétrie) |
| Tags : | Microcalorimetry Macromolecules Biological structures -- Physical basis |
| Résumé : |
The book introduces readers to the basics of thermodynamics as it applies to calorimetry, the evolution of the calorimetric technique, as well as how calorimetric techniques are used in the thermodynamic studies of macromolecules. The book covers: The use of supersensitive calorimetric instruments, including micro and nano-calorimeters for measuring the heat of isothermal reactions (Isothermal Titration Nano-Calorimeter), the heat capacities over a broad temperature range (Scanning Nano-Calorimeter), and pressure effects (Pressure Perturbation Nano-Calorimeter). Two of the simplest but key structural elements: the α and polyproline helices and their complexes, the α-helical coiled-coil, and the pyroline coiled-coils. Complicated macromolecular formations, including small globular proteins, multidomain proteins and their complexes, and nucleic acids. Numerous examples of measuring the ground state of protein energetics, as well as changes seen when proteins interact... |
| Note de contenu : |
Summary :
1. Introduction 2. Methodology 3. Calorimetry 4. Macromolecules 5. The α-helix and α-helical coiled-coil 6. Polyproline-ii coiled-coils 7. Globular proteins 8. Energetic basis of protein structure 9. Protein folding 10. Multidomain proteins 11. Macromolecular complexes 12. Protein–DNA interaction 13. Nucleic acids |
Exemplaires (2)
| Cote | Support | Localisation | Section | Disponibilité | Etat_Exemplaire |
|---|---|---|---|---|---|
| 536.6 PRI | Papier | Bibliothèque Centrale | Biologie | Disponible | Consultation sur place |
| 536.6 PRI | Papier | Bibliothèque Centrale | Biologie | Disponible | En bon état |
