| Titre : |
Nanotoxicity : from in vivo and in vitro models to health risks |
| Type de document : |
texte imprimé |
| Auteurs : |
Sahu, Saura C., Éditeur scientifique ; Casciano, Daniel A., Éditeur scientifique |
| Editeur : |
New York : John Wiley & Sons |
| Année de publication : |
2009 |
| Importance : |
609 p. |
| Présentation : |
ill. |
| Format : |
25 cm |
| ISBN/ISSN/EAN : |
978-0-470-74137-5 |
| Note générale : |
Réf. bibliogr. -Index |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Matériaux nanostructurés -- Toxicologie
Tests de toxicité
Nanostructured materials -- Toxicology
Toxicity testing
Nanostructures -- toxicity
Models, Animal
Nanotechnology
Risk Assessment |
| Index. décimale : |
615.9 Toxicologie en général. Etude des produits toxiques et des poisons. Intoxication |
| Résumé : |
Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials.
Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include:
* biomarkers for nanotoxicity assessment
* nanotoxicity assessment by gene expression analysis
* in vivo and in vitro models for nanotoxicity testing
* mechanisms of nanotoxicity
* pharmakokinetics of nanomaterials
* nanotoxicity of foods including food processing, food packaging and food safety
* nanotoxicity of drugs including drug development and drug delivery
* nanotoxicity of cosmetics and consumer products
* health and environmental impact of nanotoxicity
* safety evaluation of nanomaterials
* regulatory impact of nanomaterials
Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.
|
| Note de contenu : |
In summary :
1. Characterization of Nanomaterials for Toxicological Evaluation (Kevin W. Powers, Maria Palazuelos, Scott C. Brown and Stephen M. Roberts).
2. Criteria and Implementation of Physical and Chemical Characteristics of Nanomaterials for Human Health Effects and Ecological Toxicity Studies (Christie M. Sayes and David B. Warheit).
3. Considerations for the Design of Toxicity Studies of Inhaled Nanomedicines (Lea Ann Dailey).
4. High Aspect Ratio Nanoparticles and the Fibre Pathogenicity Paradigm (Craig A. Poland, Rodger Duffin and Ken Donaldson).
5. Application of Zinc Oxide Quantum Dots in Food Safety (Tony Jin, Dazhi Sun, Howard Zhang and Hung-Jue Sue).
6. Evaluation of Nanotoxicity of Foods and Drugs: Biological Properties of Red Elemental Selenium at Nano Size (Nano-Se) In Vitro and In Vivo (Jinsong Zhang).
7. Evaluation of Toxicity of Nanostructures in Biological Systems (Adam J. Gormley and Hamidreza Ghandehari).
8. Developing Bioassay Methods for Evaluating Pulmonary Hazards from Nanoscale or Fine Quartz/Titanium Dioxide Particulate Materials (David B. Warheit, Kenneth L. Reed and Christie M. Sayes).
9. Nanoparticles: Is Neurotoxicity a Concern? (Jianyong Wang, Wenjun Sun and Syed F. Ali).
10. Hepatotoxic Potential of Nanomaterials. |
Nanotoxicity : from in vivo and in vitro models to health risks [texte imprimé] / Sahu, Saura C., Éditeur scientifique ; Casciano, Daniel A., Éditeur scientifique . - New York : John Wiley & Sons, 2009 . - 609 p. : ill. ; 25 cm. ISBN : 978-0-470-74137-5 Réf. bibliogr. -Index Langues : Anglais ( eng)
| Mots-clés : |
Matériaux nanostructurés -- Toxicologie
Tests de toxicité
Nanostructured materials -- Toxicology
Toxicity testing
Nanostructures -- toxicity
Models, Animal
Nanotechnology
Risk Assessment |
| Index. décimale : |
615.9 Toxicologie en général. Etude des produits toxiques et des poisons. Intoxication |
| Résumé : |
Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials.
Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include:
* biomarkers for nanotoxicity assessment
* nanotoxicity assessment by gene expression analysis
* in vivo and in vitro models for nanotoxicity testing
* mechanisms of nanotoxicity
* pharmakokinetics of nanomaterials
* nanotoxicity of foods including food processing, food packaging and food safety
* nanotoxicity of drugs including drug development and drug delivery
* nanotoxicity of cosmetics and consumer products
* health and environmental impact of nanotoxicity
* safety evaluation of nanomaterials
* regulatory impact of nanomaterials
Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.
|
| Note de contenu : |
In summary :
1. Characterization of Nanomaterials for Toxicological Evaluation (Kevin W. Powers, Maria Palazuelos, Scott C. Brown and Stephen M. Roberts).
2. Criteria and Implementation of Physical and Chemical Characteristics of Nanomaterials for Human Health Effects and Ecological Toxicity Studies (Christie M. Sayes and David B. Warheit).
3. Considerations for the Design of Toxicity Studies of Inhaled Nanomedicines (Lea Ann Dailey).
4. High Aspect Ratio Nanoparticles and the Fibre Pathogenicity Paradigm (Craig A. Poland, Rodger Duffin and Ken Donaldson).
5. Application of Zinc Oxide Quantum Dots in Food Safety (Tony Jin, Dazhi Sun, Howard Zhang and Hung-Jue Sue).
6. Evaluation of Nanotoxicity of Foods and Drugs: Biological Properties of Red Elemental Selenium at Nano Size (Nano-Se) In Vitro and In Vivo (Jinsong Zhang).
7. Evaluation of Toxicity of Nanostructures in Biological Systems (Adam J. Gormley and Hamidreza Ghandehari).
8. Developing Bioassay Methods for Evaluating Pulmonary Hazards from Nanoscale or Fine Quartz/Titanium Dioxide Particulate Materials (David B. Warheit, Kenneth L. Reed and Christie M. Sayes).
9. Nanoparticles: Is Neurotoxicity a Concern? (Jianyong Wang, Wenjun Sun and Syed F. Ali).
10. Hepatotoxic Potential of Nanomaterials. |
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