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Searching for molecular solutions / Ian.s Dunn

Public ISBD Titre : Searching for molecular solutions : empirical discovery and its future Type de document : texte imprimé Auteurs : Ian.s Dunn, Auteur Editeur : New York : Wiley Année de publication : 2010 Importance : XIX, 458 p. Présentation : ill. Format : 24 cm ISBN/ISSN/EAN : 978-0-470-14682-8 Note générale : Glossary. - Bibliogr. p.374-439. - Index Langues : Anglais (eng) Mots-clés : Biochimie  --  Recherche Médicaments  --  Conception Index. décimale : 612 Physiologie. Physiologie humaine et physiologie comparée. Résumé : Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies. Along with a broad overview of the subject matter, Searching for Molecular Solutions explores * The differing modes of molecular discovery * Biological precedents for evolutionary approaches * Directed evolutionary methods and related areas * Enzyme evolution and design * Functional nucleic acid discovery * Antibodies and other recognition molecules * General aspects of molecular recognition * Small molecule discovery approaches * Rational molecular design * The interplay between empirical and rational strategies and their ongoing roles in the future of molecular discovery Searching for Molecular Solutions covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspectsof molecular discovery, as well as the thought processes behind experimental approaches. Note de contenu : Summary of the book : 1. If It Works, it Works: Pragmatic Molecular Discovery 2. Empirical Miracles: Nature’s Precedents for Empirical Solutions 3. Evolution’s Gift: Natural Somatic Diversification and Molecular Design 4. Evolution While You Wait 5. The Blind Protein Maker 6. The Blind Shaper of Nucleic Acids 7. Evolving and Creating Recognition Molecules 8. Molecules Small and Large 9. An Empirical-Rational Loop Forwards 10. Exploring the Limits Searching for molecular solutions : empirical discovery and its future [texte imprimé] / Ian.s Dunn, Auteur . - New York : Wiley, 2010 . - XIX, 458 p. : ill. ; 24 cm. ISBN : 978-0-470-14682-8 Glossary. - Bibliogr. p.374-439. - Index Langues : Anglais (eng) Mots-clés : Biochimie  --  Recherche Médicaments  --  Conception Index. décimale : 612 Physiologie. Physiologie humaine et physiologie comparée. Résumé : Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery. Logically arranged, this text examines the different modes of molecular discovery, empha-sizing the historical and ongoing importance of empirical strategies. Along with a broad overview of the subject matter, Searching for Molecular Solutions explores * The differing modes of molecular discovery * Biological precedents for evolutionary approaches * Directed evolutionary methods and related areas * Enzyme evolution and design * Functional nucleic acid discovery * Antibodies and other recognition molecules * General aspects of molecular recognition * Small molecule discovery approaches * Rational molecular design * The interplay between empirical and rational strategies and their ongoing roles in the future of molecular discovery Searching for Molecular Solutions covers several major areas of modern research, development, and practical applications of molecular sciences. This text offers empirical-rational principles of broad relevance to scientists, professionals, and students interested in general aspectsof molecular discovery, as well as the thought processes behind experimental approaches. Note de contenu : Summary of the book : 1. If It Works, it Works: Pragmatic Molecular Discovery 2. Empirical Miracles: Nature’s Precedents for Empirical Solutions 3. Evolution’s Gift: Natural Somatic Diversification and Molecular Design 4. Evolution While You Wait 5. The Blind Protein Maker 6. The Blind Shaper of Nucleic Acids 7. Evolving and Creating Recognition Molecules 8. Molecules Small and Large 9. An Empirical-Rational Loop Forwards 10. Exploring the Limits

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053313	612 DUN	Papier	Bibliothèque Centrale	Biologie	Disponible	Consultation sur place
054354	612 DUN	Papier	Bibliothèque Centrale	Biologie	Disponible	En bon état